Objective of Learning: To understand the biological mechanism of mosquito bite itch and the technical applicability of a topical formulation originally labeled for cracked skin.
ANALYTICAL FRAMEWORK
● Applicability: Partial.
● The justification lies in the presence of menthol and bisabolol, which generate cooling and soothing actions that reduce itch perception.
● Indication labeled for cracked skin: Yes / Indication labeled for mosquito bites: No, indirect/adyuvant use.
● Role: adyuvant.
● Does not replace antihistamines, corticosteroids, or calamine-based treatments.
● Applicability: Partial. 🧴
● The product identified is Kruidvat Klovenzalf, a formulation designed for dry and cracked skin.
● Its active profile includes urea, glycerin, lanolin, petrolatum, paraffinum liquidum, menthol, camphor, aloe vera, bisabolol, and horse chestnut seed extract.
● Menthol provides temporary freshness that masks itch perception, while bisabolol acts as an anti-irritant. ❄️
● Camphor behaves as a counterirritant by modulating sensory nerve signals.
● Urea, glycerin, and lanolin restore hydration and elasticity to the epidermis.
● Itch: Addressed Yes.
● Inflammation: Addressed Partial. 🌿
INSTITUTIONAL ATTRIBUTION
● The commercial name Kruidvat Klovenzalf derives from Dutch, where “kloven” means cracks and “zalf” means ointment.
● The etymological meaning defines the product as an ointment against skin cracks.
● The institutional distributor is Kruidvat, based in Renswoude, Netherlands, with the declared address Nijborg 17, 3927 DA Renswoude. 🏢
● The website provided is http://www.kruidvat.nl.
● The package volume is 75 ml and the labeled shelf life is 12 months after opening. ⏳
● Warnings include avoidance of eye and mucous contact, and restricted access for children. ⚠️
● The biological explanation of itch is anchored in the immune release of histamine after mosquito saliva injection.
● Histamine dilates vessels, triggers inflammation, and activates nerve receptors causing itch.
● The clinical symptom is worsened by scratching, which enhances inflammation and infection risk. 🧬
● The technical conclusion defines the product as adyuvant, with Partial Applicability to mosquito bite itch.
● Applicability: Partial.
● Itch: Addressed Yes.
● Inflammation: Addressed Partial. 🎯
My Diary - Leonardo Cardillo 